The effect of the freezing / thawing of the ova in their chromosomal health remained a mystery for the ova that are being frozen in an IVF program. The research conducted concerning the study of the chromosomal health of the embryos generated from frozen eggs is limited.
A new recent study elucidates the specific field of clinical embryology and IVF. In this study (Chamayou et al., 2017) 591 thawed eggs and 463 fresh eggs were used in a preimplantation genetic diagnosis for aneploidy screening program (PGD-A) for ICSI and the blastocysts created, were analyzed by the method of next generation sequencing (NGS).
The results were impressive: there was found no statistically significant difference between the two study groups on the chromosomal health of the embryos which were created, while the pregnancy and implantation rates of the embryos produced were identical in the two groups. Additionally, the ova collection via freezing for the patients, increased the available number of embryos evaluated chromosomally and hence the available number of healthy embryos for embryo transfer.
The ova collection via freezing using the most effective method of vitrification is a protocol implemented with great success at Embryogenesis during the last decade.
This method is very important in order to achieve pregnancies, especially in cases in which patients have reduced ovarian reserve, high FSH, low AMH or poor response to gonadotropins during the ovarian stimulation.
Patients belonging to the above categories could contact Embryogenesis in order to be informed about the excellent results of the unit using the above protocol.
Konstantinos A. Economou Msc, CCE
Senior Clinical Embryologist
Embryo/oocyte biopsy specialist